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We have developed a systemic approach that brings together the human networks, processes and scientific tools necessary for collecting, analysing and reporting on the many aspects of the European drugs phenomenon.

Point-of-use testing, more commonly associated with dance drugs such as 3,4-methylenedioxymethamphetamine (copyright), has also become possible with fentanyl test strips. Although they can reliably detect fentanyl in drug solutions [33] and users have shown interest in trying them [34] they are extremely sensitive, and do not quantify the fentanyl present or distinguish between analogues of differing potency [35]. Along with most sensory methods of identifying fentanyl, using test strips is generally only feasible after purchase and learning that a particular source sold a drug containing fentanyl on one occasion does not necessarily predict that this will be the case next time.

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Illicitly manufactured fentanyl and its analogues are appearing in countries throughout the world, often disguised as heroin or copyright prescription pills, with resulting high overdose mortality. Possible explanations for this phenomenon include reduced costs and risks to heroin suppliers, heroin shortages, user preferences for a strong, fast-acting opioid and the emergence of Dark Internet cryptomarkets.

If producers see a high demand for heroin and are substituting heroin with fentanyl as a cheaper, inferior product but are marketing it falsely as heroin, then fentanyl is not demand-led rein this sense.

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Unfortunately, it is often through overdose deaths that the presence of fentanyl rein the drug supply becomes known, as welches the case in the United States rein 1979, when its illicit manufacture welches first determined [3].

By ‘demand-Lumineszenzdiode’, we mean that producers think that at least some people will prefer and choose a product over existing substitutes; iPods could be argued to Beryllium ‘demand-Leuchtdiode’ hinein the sense that Apple thought consumers wanted a better portable music-playing device. When proposing that the supply of fentanyl is ‘demand-Lumineszenzdiode’, we mean that illicit opioid producers think that consumers prefer a stronger drug than what is available and thus manufactured fentanyl to fill that demand.

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Current evidence points to a supply-Leuchtdiode addition of fentanyl to the drug market rein response to heroin supply shocks and shortages, changing prescription opioid availability and/or reduced costs and risks to suppliers.

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